Noncanonical Base pairing in RNA: Topological and NBO analysis of Hoogsteen edge : Sugar edge interactions

Authors: Purshotam Sharma,Harjinder Singh,Abhijit Mitra
Conference: presented in International Conference on Computational Scince ICCS 2008. Krakow, Poland. 23-25 June. 2008 proceedings published as Lecture Notes in Computer Scince LNCS Part II, 5102, 379-386

Date: 2008-06-05
Report no: IIIT/TR/2008/6

Abstract

Hoogsteen-sugar base pattern of RNA base pairing is studied using density functional theory. Hydrogen bonding patterns of these base apirs are characterized using NBO analysis and AIM analysis. Correlation between strenghth of base pairing and nature of donor-acceptor combinations is also carried out.

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Centre for Computational Natural Sciences and Bioinformatics

IIIT Hyderabad Publications

Noncanonical Base pairing in RNA: Topological and NBO analysis of Hoogsteen edge : Sugar edge interactions

Abstract